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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T71399 | Plogosertib | CYC140 | |
Plogosertib (CYC140), a selective and potent orally active ATP-competitive PLK1 inhibitor (IC 50: 3 nM), functions as an anticancer agent with antiproliferative effects. It is utilized in the research of various tumors s... | |||
T2066 | Quizartinib | AC220 | Apoptosis , FLT , Autophagy , Ligands for Target Protein for PROTAC |
Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases. |